body {
    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Arial, 'Noto Sans SC', 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei', sans-serif;
    margin: 0;
    display: flex;
    flex-direction: column;
    align-items: center;
    min-height: 100vh;
}

header h1 { margin: 0 0 12px; }
nav a { margin-right: 12px; text-decoration: none; }
.card { background: #fff; padding: 16px; border: 1px solid #e5e7eb; border-radius: 12px; box-shadow: 0 1px 3px rgba(0,0,0,.06); }
button { padding: 8px 14px; border: 1px solid #2563eb; background: #3b82f6; color: #fff; border-radius: 8px; cursor: pointer; }
button:hover { opacity: .9; }
.table-wrapper { overflow-x: auto; }
table { border-collapse: collapse; width: 100%; }
th, td { border: 1px solid #eee; padding: 8px; text-align: left; }
.error { margin-top: 12px; color: #b91c1c; }

.guidance-main {
    display: flex;
    justify-content: center;
    align-items: center;
    flex-direction: column;
    width: 100%;
}

.model-instruction {
    font-size: 24px !important;
    font-weight: bold !important;
    text-align: left;
    width: 100%;
    margin-top: 40px;
    margin-bottom: 0px;
}

.env-vars {
    font-family: 'SimSun', serif !important;
    font-size: 20px !important;
    font-weight: normal !important;
    text-align: left;
    line-height: 0;
}

.fasta-instruction-1 {
    font-family: 'Times New Roman', serif !important;
    font-size: 24px !important;
    font-weight: bold !important;
    text-align: left;
    width: 100%;
    margin-top: 40px;
    margin-bottom: 20px;
}
.fasta-instruction-2 {
    font-family: 'Times New Roman', serif !important;
    font-size: 24px !important;
    font-weight: bold !important;
    text-align: left;
    width: 100%;
    margin-top: 40px;
    margin-bottom: 20px;
}

.guidance-box {
    width: 100%;
    background: #fff;
    border: 1px solid #e5e7eb;
    border-radius: 12px;
    box-shadow: 0 1px 3px rgba(0,0,0,.06);
    display: flex;
    flex-direction: column;
    justify-content: flex-start;
    align-items: flex-start;
    box-sizing: border-box;
    margin-bottom: 0px;
}
.guidance-box-1 {
    padding: 12px;
}
.guidance-box-2 {
    padding: 12px;
}

.guidance-list {
    width: 100%;
    padding-left: 20px;
    margin: 0;
}
.guidance-list li {
    margin-bottom: 10px;
    line-height: 1.5;
}
.guidance-list-1 li {
    font-family: 'Times New Roman', serif !important;
    font-size: 20px !important;
    font-weight: normal !important;
    text-align: justify;
}
.guidance-list-1 li:nth-child(2) {
    font-family: 'Times New Roman', serif !important;
}

main:not(.download-main) {
    display: flex;
    justify-content: center;
    align-items: center;
    flex-direction: column;
}

.notice-section {
    font-family: 'Times New Roman', serif !important;
    font-size: 22px !important;
    font-weight: bold !important;
    text-align: justify;
    line-height: 1.5;
    margin-top: 0px;
    margin-bottom: 10px;
}

.warning-icon {
    color: #ff0000;
    margin-right: 8px;
    font-size: 22px;
}

.notice-list {
    width: 100%;
    padding-left: 0;
    margin: 0;
    list-style: none;
    counter-reset: circle-counter;
}
.notice-list li {
    margin-bottom: 8px;
    line-height: 1.5;
    font-family: 'Times New Roman', serif !important;
    font-size: 20px !important;
    font-weight: normal !important;
    text-align: justify;
    position: relative;
    padding-left: 1.5em;
}
.notice-list li::before {
    counter-increment: circle-counter;
    content: "①②③④⑤⑥⑦⑧⑨⑩" counter(circle-counter);
    content: counter(circle-counter, cjk-ideographic) "";
    position: absolute;
    left: 0;
    width: 2em;
}
.notice-list li:nth-child(1)::before { content: "①"; }
.notice-list li:nth-child(2)::before { content: "②"; }
.notice-list li:nth-child(3)::before { content: "③"; }
.notice-list li:nth-child(4)::before { content: "④"; }
.notice-list li:nth-child(5)::before { content: "⑤"; }

code {
    background-color: #f8f9fa;
    padding: 2px 4px;
    border-radius: 4px;
    font-family: 'Courier New', monospace;
}

.fasta-example {
    font-family: 'Noto Serif SC ExtraLight', monospace !important;/* Courier New */
    font-size: 18px !important;
    background-color: #f8f9fa;
    width: 100%;
    padding: 8px;
    border-radius: 4px;
    margin-top: 5px;
    text-indent: 0em;
    white-space: pre-line;
    line-height: 1.4;
}

.predict-link {
    color: #3b82f6 !important;
    font-weight: bold !important;
    text-decoration: none;
}
.predict-link:hover {
    color: #2563eb !important;
    text-decoration: underline;
}
.predict-link:visited {
    color: #3b82f6 !important;
}

.guidance-list-2 li {
    font-family: 'Times New Roman';
    font-size: 20px !important;
    font-weight: normal !important;
    text-align: justify;
}
.guidance-list-2 li:nth-child(2) {
    font-family: 'Times New Roman';
    font-size: 20px !important;
}

.download-link {
    color: #3b82f6 !important;
    font-weight: bold !important;
    text-decoration: none;
}
.download-link:hover {
    color: #2563eb !important;
    text-decoration: underline;
}
.download-link:visited {
    color: #3b82f6 !important;
}

.github-link {
    color: #3b82f6 !important;
    font-weight: bold !important;
    text-decoration: none;
}
.github-link:hover {
    color: #2563eb !important;
    text-decoration: underline;
}
.github-link:visited {
    color: #3b82f6 !important;
}

.readme-link {
    color: #3b82f6 !important;
    font-weight: bold !important;
    text-decoration: none;
}
.readme-link:hover {
    color: #2563eb !important;
    text-decoration: underline;
}
.readme-link:visited {
    color: #3b82f6 !important;
}

.githubreadme-link {
    color: #3b82f6 !important;
    font-weight: bold !important;
    text-decoration: none;
}
.githubreadme-link:hover {
    color: #2563eb !important;
    text-decoration: underline;
}
.githubreadme-link:visited {
    color: #3b82f6 !important;
}